Love your translation of some of the more technical pathways. So often we gloss over how things like SCFAs or microbial-derived serotonin don’t just influence our “mood” in the abstract but are actually signaling between the gut lining, vagus nerve, and ultimately the whole neuroimmune axis. That feedback loop is real. It’s still striking to me, after years working on Parkinson’s microbiome research, how early shifts in microbial metabolites can precede symptoms by years and why even psychiatrists are starting to sit up and take notice.
Thank you! It's definitely pretty complicated, so I'm glad the translation makes sense and still holds true for someone with a lot of expertise like you.
Really interesting read...have suffered with OCD since I was a child running along concurrently with IBS which evolved into Ulcerative Colitis as an adult. Most of time I am fine and can manage my symptoms but at times of high stress or bowel infection (i have a toddler so am more likely to get stomach bugs) my OCD can become debilitating. I don't take regular pro/prebiotic but do intermittently have kefir, kombucha, sauerkraut but I might explore a supplementary approach during this high stress or sick times and see if it makes a difference
Love your translation of some of the more technical pathways. So often we gloss over how things like SCFAs or microbial-derived serotonin don’t just influence our “mood” in the abstract but are actually signaling between the gut lining, vagus nerve, and ultimately the whole neuroimmune axis. That feedback loop is real. It’s still striking to me, after years working on Parkinson’s microbiome research, how early shifts in microbial metabolites can precede symptoms by years and why even psychiatrists are starting to sit up and take notice.
Thank you! It's definitely pretty complicated, so I'm glad the translation makes sense and still holds true for someone with a lot of expertise like you.
Really interesting read...have suffered with OCD since I was a child running along concurrently with IBS which evolved into Ulcerative Colitis as an adult. Most of time I am fine and can manage my symptoms but at times of high stress or bowel infection (i have a toddler so am more likely to get stomach bugs) my OCD can become debilitating. I don't take regular pro/prebiotic but do intermittently have kefir, kombucha, sauerkraut but I might explore a supplementary approach during this high stress or sick times and see if it makes a difference
Thank you Grace, please report back if you notice any changes with probiotic supplements, I'll be interested in the results of your experiment.